Exploration of latent warheads for covalent inhibition of therapeutic proteins
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Targeting cellular redox modulations for pancreatic cancer treatment
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Targeting human base excision repair as a novel strategy in cancer therapeutics
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Systems pharmacology for acute myeloid leukemia and feedback control pharmacodynamic models
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Developing MLL1 degraders as therapeutics for leukemia
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Investigating the effects of polycomb repressive complex inhibitors on cancer cell phenotypic plasticity
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Inhibition of monoamine oxidase A and histone deacetylase inhibitors: computational prediction of ligand binding
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Optimizing small compounds to better understand tau fibril inhibition
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Mechanistic studies of novel small molecule anti-cancer agents using next generation sequencing
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Directed evolution of high affinity, cyclic, protease resistant peptides using mRNA display
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Development of selective covalent probes to identify and modulate protein targets
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I. Microwave-assisted synthesis of phosphonic acids; II. Design and synthesis of polymerase β lyase domain inhibitors
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Discovery of small molecules for brain cancer treatment
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Drug discovery for highly pathogenic hemorrhagic fever viruses
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Cardiac function in children and young adults treated with MEK inhibitors: a retrospective cohort study of routinely collected health data
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HIV-1 integrase and human APE1: two DNA-processing enzymes and two druggable targets
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Exploring the effects of CXCR4 inhibition on circulating tumor cell populations in metastatic prostate cancer
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Mechanism of a new CK2 inhibitor triggering senescence in breast cancer cells
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Multivalent smart elastin-like polypeptide therapeutics with drug delivery and biosensing applications.
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Modeling of water molecules in protein-ligand binding
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Synthetic small molecules and protein secondary structure mimetics as modulators of hypoxia-inducible transcription and integrin receptors function
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Medicinal chemistry and chemical biology approaches to improve the selectivity and potency of kinase inhibitors
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O-GlcNAc: development of new inhibitors and investigations into fibroblast contraction
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Understanding the role of BRCA1 and Aurora A kinase in polyploidy development in ovarian carcinoma precursor cells
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Cellular uptake of cyclic cystine knotted cyclotides from Momordica cochinchinesis family
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