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Deoxyribonucleoside triphosphate analogues for inhibition of therapeutically important enzymes
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Modulation of T cell responses by extracellular nucleotides
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Difluoromethylphosphonate: a versatile reagent for synthesis of novel isopolar and bioisosteric nucleotide analogues
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Synthesis of novel nucleotide analogues based on the traditional and nontraditional bioisosteres
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Systematic analysis of single nucleotide polymorphisms in the human steroid 5-alpha reductase type I gene
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Novel stereochemical probes for DNA polymerases: nucleoside triphosphate beta,gamma-CXY analogues
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Nucleotide analogs and molecular probes for LFER, time-resolved crystallography, FRET, and EPR studies of human DNA polymerase: probing mechanism, conformation and structure
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Bisphosphonates for modified nucleotide synthesis and related chemistry
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Design and synthesis of a series of methylenebisphosphonates: a nucleotide analogue toolkit to probe nucleic acid polymerase structure and function
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Fluorinated probes of enzyme mechanisms
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Studies On Cyclic Nucleotide Phosphodiesterase
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Molecular And Regulatory Properties Of Multiple Cyclic Nucleotide Phosphodiesterases
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Deoxynucleotide analog probes and model compounds for studying DNA polymerase structure and mechanism: synthesis and evaluation of alkyl-, azido-, and halomethylene bisphosphonate-substituted tri...
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Cyclic nucleotide phosphodiesterase activity in normal and transformed human lymphoid cells: Enzyme properties and regulation
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Nucleophilic fluorination of bisphosphonates and its application in PET imaging
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Synthetic studies of chemical probes for i) DNA, ii) RNA polymerases and iii) tropomyosin receptor kinase
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High performance liquid chromatography applied to the study of hormonal regulation of cyclic AMP and other adenine nucleotide levels in rat adipocytes
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Intracellular drug-drug interaction between nucleoside analogs leads to early virologic failure in HIV patients receiving triple nucleoside combinations of tenofovir, lamivudine and abacavir or d...
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Expansion of deoxynucleotide analog probes for studying DNA polymerase mechanism: synthesis of novel beta, gamma-CXY deoxycytidine series
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Regulation of ethanol intake by purinergic P2X4 receptors
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Decrypting Escherichia coli DNA polymerase V mutasome ATP regulation
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Activation mechanism of damaged-induced DNA polymerase V in Escherichia coli
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POLR2B and its contributions to cancer cell growth
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Investigating the E. Coli DNA polymerase V mutasome
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Targeting human base excision repair as a novel strategy in cancer therapeutics
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