Difluoromethylphosphonate: a versatile reagent for synthesis of novel isopolar and bioisosteric nucleotide analogues 

Fluorinated probes of enzyme mechanisms 

Modulation of T cell responses by extracellular nucleotides 

Synthesis of novel nucleotide analogues based on the traditional and nontraditional bioisosteres 

Novel stereochemical probes for DNA polymerases: nucleoside triphosphate beta,gamma-CXY analogues 

Deoxyribonucleoside triphosphate analogues for inhibition of therapeutically important enzymes 

Bisphosphonates for modified nucleotide synthesis and related chemistry 

Nucleotide analogs and molecular probes for LFER, time-resolved crystallography, FRET, and EPR studies of human DNA polymerase: probing mechanism, conformation and structure 

Deoxynucleotide analog probes and model compounds for studying DNA polymerase structure and mechanism: synthesis and evaluation of alkyl-, azido-, and halomethylene bisphosphonate-substituted tri... 

Design and synthesis of a series of methylenebisphosphonates: a nucleotide analogue toolkit to probe nucleic acid polymerase structure and function 

Accessible cytotoxic and antiviral drug analogues: improved synthetic approaches to isoindolinones and bioisosteric difluoromethylated nucleotides, and the search for therapeutic organotelluranes 

Advancing computational methods for free energy calculations in proteins and the applications for studies of catalysis in nucleotide-associated proteins 

Systematic analysis of single nucleotide polymorphisms in the human steroid 5-alpha reductase type I gene 

Synthetic studies of chemical probes for i) DNA, ii) RNA polymerases and iii) tropomyosin receptor kinase 

Nucleophilic fluorination of bisphosphonates and its application in PET imaging 

Intracellular drug-drug interaction between nucleoside analogs leads to early virologic failure in HIV patients receiving triple nucleoside combinations of tenofovir, lamivudine and abacavir or d... 

Studies on cyclic nucleotide phosphodiesterase 

Crystallographic studies of antibiotics and nucleotides 

Expansion of deoxynucleotide analog probes for studying DNA polymerase mechanism: synthesis of novel beta, gamma-CXY deoxycytidine series 

The incorporation of L-carbamyl-C14-aspartate into the acid-soluble pyrimidine nucleotides of mouse brain 

Characterization of the interaction of nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain-containing protein 12 (Nlrp12) with hematopoietic cell kinase (Hck) 

Photolabeling the nucleotide binding sites of dog kidney Na,K-ATPase with azido nucleotides 

Design and synthesis of novel nucleotide probes for DNA polymerase, DNA polymerase ribozyme, glycosyl transferase and phosphoglycosyl transferase 

Nucleotides And Enzyme Regulation: Cooperativity In Phosphorylase B And Cyclic Nucleotide Phosphodiesterase 

Molecular And Regulatory Properties Of Multiple Cyclic Nucleotide Phosphodiesterases