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Biochemistry of nonhomologous DNA end joining (NHEJ) and its role in V(D)J recombination
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Oxygen metabolism, chromosome breaks, and cell death: The role of the nonhomologous DNA end joining pathway in maintaining genomic stability
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Scanning and catalytic properties of AID with structural comparisons to APOBEC3A
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How phosphorylation affects the biochemical regulation and targeting of activation induced cytidine deaminase (AID)
Gene therapy for the prevention and treatment of leukemia
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Studies on the role of Artemis in non-homologous DNA end-joining to understand the mechanism and discover therapies
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Improving adeno-associated viral vector for hematopoietic stem cells gene therapy
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Analysis of high-density oligonucleotide gene expression data for dissecting aging pathways
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Engineering viral vectors for T-cell immunotherapy and HIV-1 vaccine
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Over-expression of superoxide dismutase in Drosophila melanogaster
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Using engineered exosomes and gene-editing to target latent HIV
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Mechanism of human nonhomologous DNA end joining
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Investigation of two distinct chromatin events: H3 tail-mediated factor recruitment and H2A.X exchange
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Molecular misreading in Drosophila melanogaster
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A structure based study of the HIV restriction factor APOBEC3G
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Studies of the biological relevance of Histone H4 Lysine 20 monomethylation: discovery of its role in the cell cycle and localization within the human genome
The mechanism of mammalian immunoglobulin class switch recombination: R-loop structures and activation-induced deaminase site preferences
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Characterizing and manipulating homology-directed gene editing in human cells
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Meat intake, polymorphisms in the NER and MMR pathways and colorectal cancer risk
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The role of SNPs in NER and MMR pathways in the modification of role of cooked meats on colorectal cancer
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Measuring, modeling and identifying factors that influence eukaryotic DNA replication
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A regulatory transcription module of ZBRK1/KAP1 complex and its signaling network in regulating DNA damage-responsive genes expression
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Engineering viral vectors for gene and cell targeting
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