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Chemical dissection of monosaccharide metabolic chemical reporter selectivity
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Development of metabolic chemical reporters for the investigation of protein glycosylation
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SGLT2 inhibitors reverse adipocyte differentiation and reduce daunorubicin metabolism in acute lymphoblastic leukemia treatment
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Discovery of new HIV-1 integrase inhibitors
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Discovery of a novel HIV-1 integrase inhibitor binding site: insight into enzyme structure/function and inhibitor design
Factors that may impact drug disposition and metabolism
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Optimization of chemical reporters of O-GlcNAc for improved specificity and metabolic mapping
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DNA methylation inhibitors and epigenetic regulation of microRNA expression
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Synthetic and metabolic studies of deuterium labelled drugs
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Dissecting metabolic changes in muscle stem cells during activation
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Synthesis of protein-protein interaction inhibitors and development of new catalytic methods
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Effects of a GSK-3 inhibitor on retroviral-mediated gene transfer to human CD34+ hematopoietic progenitor cells
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Discovery of novel small molecules targeting cancer cell metabolism
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Chemical probes of protein tyrosine phosphatase activity
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O-GlcNAc: development of new inhibitors and investigations into fibroblast contraction
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Genetic manipulation of receptor interacting protein (RIP140) uncovers its critical role in the regulation of metabolism, gene expression and insulin signaling in skeletal muscle cells
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WDR23-mediated regulation of the DNA damage response, oxidative stress resistance, and glucose metabolism
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System biology approaches to cancer and diabetes metabolism
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The differential effects of genistein on cellular effects in T47D tumorigenic and MCF10A nontumorigenic breast epithelial cells: role of metabolism
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Screening of cysteine-rich backbone cyclized peptide libraries for inhibitors against disease-related proteases
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C-jun N-terminal Kinase (JNK) mediated inhibition of Pyruvate Dehydrogenase (PDH) activity and its effect on mitochondrial metabolism during brain aging
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The contribution of chemical steps to DNA polymerase beta catalysis and fidelity
Dissecting novel roles for MAFR-1 in reproduction and metabolic homeostasis
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Inhibition of monoamine oxidase A and histone deacetylase inhibitors: computational prediction of ligand binding
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The use of metabolic inhibitors in the correlation of function and metabolism of cardiac muscle
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