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The biochemical characterization of activation induced cytidine deaminase
Scanning and catalytic properties of AID with structural comparisons to APOBEC3A
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How phosphorylation affects the biochemical regulation and targeting of activation induced cytidine deaminase (AID)
Hutchinson Gilford progeria syndrome and the role of lamin A in the onset of the progeroid cellular phenotype
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In silico enzyme modeling: A study of entropic contributions to enzyme catalysis and the design of artificial kemp eliminase
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Structural studies of two key factors for DNA replication in eukaryotic cells
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Studies on the role of Artemis in non-homologous DNA end-joining to understand the mechanism and discover therapies
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DNA methylation inhibitors and epigenetic regulation of microRNA expression
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A structure based study of the HIV restriction factor APOBEC3G
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The mechanism of mammalian immunoglobulin class switch recombination: R-loop structures and activation-induced deaminase site preferences
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Structural and biochemical analyses on substrate specificity and HIV-1 Vif mediated inhibition of human APOBEC3 cytidine deaminases
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Factors impacting drug disposition and clinical outcomes: age, hepatic metabolism, renal elimination and pharmacogentetics
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Molecular genetic analysis of human genetic lesions
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Pre-B cell receptor signaling in acute lymphoblastic leukemia
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Role of TLR4 and AID in lymphomagenesis induced by obesity and hepatitis C virus
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The crystal structure of APOBEC-2 and implications for APOBEC enzymes
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Genetic risk factors in multiple myeloma
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Synergism between TLR4-c-JUN axis and surface receptor stimulation translocate c-MYC into Ig loci, through AID leading to lymphomagenesis
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The mechanism of R-loop formation in mammalian immunoglobulin class switch recombination
Role of DNA methyltransferases 3A and 3B in inheritance of DNA methylation patterns
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Molecular mechanisms of recurrent chromosomal translocations in human leukemias and lymphomas
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Structural and biochemical determinants of APOBEC1 substrate recognition and enzymatic function
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Use of DNA methylation inhibitors for chemotherapy and chemoprevention of cancer
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