Physiological roles and evolutionary implications of alternative DNA polymerases in Escherichia coli 

Investigating the E. Coli DNA polymerase V mutasome 

Activation mechanism of damaged-induced DNA polymerase V in Escherichia coli 

Design and synthesis of novel nucleotide probes for DNA polymerase, DNA polymerase ribozyme, glycosyl transferase and phosphoglycosyl transferase 

Expansion of deoxynucleotide analog probes for studying DNA polymerase mechanism: synthesis of novel beta, gamma-CXY deoxycytidine series 

The contribution of chemical steps to DNA polymerase beta catalysis and fidelity 

Synthetic studies of chemical probes for i) DNA, ii) RNA polymerases and iii) tropomyosin receptor kinase 

Decrypting Escherichia coli DNA polymerase V mutasome ATP regulation 

Mechanism of human nonhomologous DNA end joining 

Design and synthesis of a series of methylenebisphosphonates: a nucleotide analogue toolkit to probe nucleic acid polymerase structure and function 

Structural and biochemical studies of large T antigen: the SV40 replicative helicase 

DNA polymerase mechanism and fidelity: using β,γ-bridging oxygen substituted dNTPs to study the mechanism of DNA polymerase β 

Decoding protein-DNA binding determinants mediated through DNA shape readout 

Design and synthesis of phosphonates as inhibitors and agonists 

Novel stereochemical probes for DNA polymerases: nucleoside triphosphate beta,gamma-CXY analogues 

X-ray structural studies on DNA-dependent protein kinase catalytic subunit:DNA co-crystals 

Nucleotide analogs and molecular probes for LFER, time-resolved crystallography, FRET, and EPR studies of human DNA polymerase: probing mechanism, conformation and structure 

Genetic diversity and bacterial death in the context of adaptive evolution 

Deoxynucleotide analog probes and model compounds for studying DNA polymerase structure and mechanism: synthesis and evaluation of alkyl-, azido-, and halomethylene bisphosphonate-substituted tri... 

Generation of monoclonal antibodies via phage display and in vitro affinity maturation using activation induced deoxycytidine deaminase and DNA polymerase eta 

Current models of non-homologous end joining and their implications in gene therapy 

Mechanistic basis for chromosomal translocations at the E2A gene 

Studies on the alteration of dna methylation in cancer 

Studies on the role of Artemis in non-homologous DNA end-joining to understand the mechanism and discover therapies 

Mechanisms of nucleases in non-homologous DNA end joining