Rational selection of CRISPR/Cas9 guide RNAs for homology directed genome editing and its utility in the development of gene therapies
PDF
Quantifying aspects of DNA damage
PDF
Site-directed spin labeling studies of sequence-dependent DNA shape and protein-DNA recognition
PDF
Understanding protein–DNA recognition in the context of DNA methylation
PDF
Characterizing and manipulating homology-directed gene editing in human cells
PDF
Machine learning of DNA shape and spatial geometry
PDF
Current models of non-homologous end joining and their implications in gene therapy
PDF
Site-directed spin labeling studies of target DNA recognition by a CRISPR nuclease
PDF
Exploring roles of human APOBEC-mediated RNA editing activity
PDF
Photocontrol of DNA compaction using light-responsive surfactants
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Genome-wide studies of protein–DNA binding: beyond sequence towards biophysical and physicochemical models
PDF
DNA methylation as a biomarker in human reproductive health and disease
PDF
Studies on the role of Artemis in non-homologous DNA end-joining to understand the mechanism and discover therapies
PDF
DNA methylation changes in the development of lung adenocarcinoma
PDF
Structural and biochemical analyses on substrate specificity and HIV-1 Vif mediated inhibition of human APOBEC3 cytidine deaminases
PDF
Functional DNA methylation changes in normal and cancer cells
PDF
Ultrafast electronic deactivation of DNA bases in aqueous solution
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Expansion of deoxynucleotide analog probes for studying DNA polymerase mechanism: synthesis of novel beta, gamma-CXY deoxycytidine series
PDF
Physiological roles and evolutionary implications of alternative DNA polymerases in Escherichia coli
PDF
Using engineered exosomes and gene-editing to target latent HIV
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Structural studies of two key factors for DNA replication in eukaryotic cells
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Mechanisms of nucleases in non-homologous DNA end joining
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Understanding DNA methylation and nucleosome organization in cancer cells using single molecule sequencing
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The C3ORF37/SRAP1: a candidate tumor suppressor that promotes removal of methylated DNA
PDF
Mechanistic basis for chromosomal translocations at the E2A gene
PDF
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