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17
Lung and Bronchus
288
2.7%
1,627
15.0%
8,934
82.3%
--
--
--
0
2
50.0%
2
50.0%
Bones and Joints
3,595
36.8%
3,483
35.7%
2,686
27.5%
--
--
--
4
80.0%
1
20.0%
0
0%
Urinary Bladder, invasive and in situ
229
2.7%
1,601
18.6%
6,758
78.7%
164
8.2%
755
38.0%
1,070
53.8%
0
0%
1
33.3%
2
66.7%
Kaposi Sarcoma
41
0.5%
1,972
25.7%
5,674
73.8%
--
--
--
--
--
--
Stomach
97
1.5%
1167
18.5%
5,033
79.9%
--
--
--
0
0%
1
50.0%
1
50.0%
Tongue
65
1.6%
873
21.6%
3,097
76.8%
--
--
--
--
--
--
Pancreas
82
2.1%
542
13.6%
3,370
84.4%
--
--
--
--
--
--
Liver
261
6.7%
945
24.4%
2,661
68.8%
--
--
--
--
--
--
Myeloma
22
0.7%
319
10.9%
2,598
88.4%
--
--
--
--
--
--
Salivery Gland
311
10.8
849
29.5
1,715
59.7
--
--
--
--
--
--
Other
2,768
7.2%
8,929
23.3%
26,599
69.5%
--
--
--
2
16.7%
5
41.7%
5
41.7%
Unspecifiedd
--
--
--
--
--
--
5
10.9%
15
32.6%
26
56.6%
Totale
44,457
1.0%
156,642
34.0%
299,477
65.0%
--
--
--
34
17.3%
59
29.9%
104
52.8%
a Data are from selected statewide and metropolitan area cancer registries, 1999-2016, United States of America, ages 15-39, CDC WONDER
b Data are estimated number of prevalent cases in 2018 within a 5-year period, United States of America, ages 15-39, CANCER TODAY
c Data are collected by Medical Expenditure Panel Surveys (MEPs), 2008-2012, United States of America, ages 15-39
d In MEPs, other cancer includes those cancer diagnosis variables with a frequency count of fewer than 4 from 2008 to 2011. Since 2012, those cancer diagnosis variables with a frequency count of fewer than 20 were recorded as other cancer for confidential reasons.
Object Description
| Title | A comparison of three different sources of data in assessing the adolescent and young adults cancer survivors |
| Author | Chen, Irene Jiayao |
| Author email | jiayaoch@usc.edu;jiayaoch@usc.edu |
| Degree | Master of Science |
| Document type | Thesis |
| Degree program | Applied Biostatistics and Epidemiology |
| School | Keck School of Medicine |
| Date defended/completed | 2020-08-07 |
| Date submitted | 2020-08-07 |
| Date approved | 2020-08-08 |
| Restricted until | 2020-08-08 |
| Date published | 2020-08-08 |
| Advisor (committee chair) | Cortessis, Victoria |
| Advisor (committee member) |
Miller, Kimberly Farias, Albert |
| Abstract | Relatively limited data resources are available to study Adolescent and Young Adults (AYA) cancers. We created an AYA cancer survivor cohort by identifying survivors (N=1,142) who were 15 to 39 years of age at the time of their first cancer diagnosis, excluding diagnoses of nonmelanoma skin cancers. We characterized the occurrence of incident cancers in the CDC WONDER, prevalent cancers in the Cancer Today and AYA MEPS according to the absolute number and relative frequency of primary cancers diagnosed at ages 15-39 years of age. We compared the distribution of demographic features and cancer types between the three data resources concerning relative frequency. We found an enormous distortion of the sex ratio of survivors, with female cancer survivors overrepresented. Among females diagnosed in the AYA age range, there was a clear overrepresentation of reproductive cancers, such as cervical, ovarian, and corpus uterus. The numerous limitations of MEPS AYA cohort data, lack of representativeness, inaccuracies in the diagnostic data, and readily anticipated based on methodology, emphasize the need for a nationally representative data resource of AYA cancers. |
| Keyword | adolescent and young adult cancers; diagnostic data; limitations |
| Language | English |
| Part of collection | University of Southern California dissertations and theses |
| Publisher (of the original version) | University of Southern California |
| Place of publication (of the original version) | Los Angeles, California |
| Publisher (of the digital version) | University of Southern California. Libraries |
| Provenance | Electronically uploaded by the author |
| Type | texts |
| Legacy record ID | usctheses-m |
| Contributing entity | University of Southern California |
| Rights | Chen, Irene Jiayao |
| Physical access | The author retains rights to his/her dissertation, thesis or other graduate work according to U.S. copyright law. Electronic access is being provided by the USC Libraries in agreement with the author, as the original true and official version of the work, but does not grant the reader permission to use the work if the desired use is covered by copyright. It is the author, as rights holder, who must provide use permission if such use is covered by copyright. The original signature page accompanying the original submission of the work to the USC Libraries is retained by the USC Libraries and a copy of it may be obtained by authorized requesters contacting the repository e-mail address given. |
| Repository name | University of Southern California Digital Library |
| Repository address | USC Digital Library, University of Southern California, University Park Campus MC 7002, 106 University Village, Los Angeles, California 90089-7002, USA |
| Repository email | cisadmin@lib.usc.edu |
| Filename | etd-ChenIreneJ-8901.pdf |
| Archival file | Volume13/etd-ChenIreneJ-8901.pdf |
Description
| Title | Page 22 |
| Full text | 17 Lung and Bronchus 288 2.7% 1,627 15.0% 8,934 82.3% -- -- -- 0 2 50.0% 2 50.0% Bones and Joints 3,595 36.8% 3,483 35.7% 2,686 27.5% -- -- -- 4 80.0% 1 20.0% 0 0% Urinary Bladder, invasive and in situ 229 2.7% 1,601 18.6% 6,758 78.7% 164 8.2% 755 38.0% 1,070 53.8% 0 0% 1 33.3% 2 66.7% Kaposi Sarcoma 41 0.5% 1,972 25.7% 5,674 73.8% -- -- -- -- -- -- Stomach 97 1.5% 1167 18.5% 5,033 79.9% -- -- -- 0 0% 1 50.0% 1 50.0% Tongue 65 1.6% 873 21.6% 3,097 76.8% -- -- -- -- -- -- Pancreas 82 2.1% 542 13.6% 3,370 84.4% -- -- -- -- -- -- Liver 261 6.7% 945 24.4% 2,661 68.8% -- -- -- -- -- -- Myeloma 22 0.7% 319 10.9% 2,598 88.4% -- -- -- -- -- -- Salivery Gland 311 10.8 849 29.5 1,715 59.7 -- -- -- -- -- -- Other 2,768 7.2% 8,929 23.3% 26,599 69.5% -- -- -- 2 16.7% 5 41.7% 5 41.7% Unspecifiedd -- -- -- -- -- -- 5 10.9% 15 32.6% 26 56.6% Totale 44,457 1.0% 156,642 34.0% 299,477 65.0% -- -- -- 34 17.3% 59 29.9% 104 52.8% a Data are from selected statewide and metropolitan area cancer registries, 1999-2016, United States of America, ages 15-39, CDC WONDER b Data are estimated number of prevalent cases in 2018 within a 5-year period, United States of America, ages 15-39, CANCER TODAY c Data are collected by Medical Expenditure Panel Surveys (MEPs), 2008-2012, United States of America, ages 15-39 d In MEPs, other cancer includes those cancer diagnosis variables with a frequency count of fewer than 4 from 2008 to 2011. Since 2012, those cancer diagnosis variables with a frequency count of fewer than 20 were recorded as other cancer for confidential reasons. |
