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DYNAMIC ANALYSES OF COGNITION AND MORTALITY
IN THE OLDEST OLD
by
Yan Zhou
A Dissertation Presented to the
FACULTY OF THE USC GRADUATE SCHOOL
UNIVERSITY OF SOUTHERN CALIFORNIA
In Partial Fulfillment of the
Requirements for the Degree
DOCTOR OF PHILOSOPHY
(PSYCHOLOGY)
August 2011
Copyright 2011 Yan Zhou
Object Description
| Title | Dynamic analyses of cognition and mortality in the oldest old |
| Author | Zhou, Yan |
| Author email | zhou5@usc.edu;zhouyannb@gmail.com |
| Degree | Doctor of Philosophy |
| Document type | Dissertation |
| Degree program | Psychology |
| School | College of Letters, Arts And Sciences |
| Date defended/completed | 2011-05-04 |
| Date submitted | 2011-07-17 |
| Date approved | 2011-07-18 |
| Restricted until | 2011-07-18 |
| Date published | 2011-07-18 |
| Advisor (committee chair) | McArdle, John J. |
| Advisor (committee member) |
John, Richard S. Walsh, David A. Wilcox, Rand R. Silverstein, Merril |
| Abstract | This study examined the interrelations between cognition and mortality in a nationally representative sample of the U.S. population aged 70 and older. A distinct feature of this dataset is the gradual passing away of the participants over seven waves of longitudinal data collection (1993-2006). To account for this particular type of attrition in the modeling of longitudinal cognitive data, three different statistical models were used: latent curve models, change point models, and joint growth and survival models. After these, survival times for these participants were predicted using traditional survival analysis and exploratory data mining including survival trees and random forests. The results showed that episodic memory declined considerably with age, while crystallized intelligence was largely stable until about age 77 and even the decline after this point was relatively slow, which was in agreement with the aging theory of intellectual abilities (Horn & Cattell, 1966). There did not seem to be a death-driven process that was related to the deterioration in these two abilities. Consistent with many earlier findings, cognitive levels were found to be negatively associated with mortality for both episodic memory and crystallized intelligence, but only the memory slope was found to be associated with mortality. Results from different methods consistently demonstrated that cognition was a useful predictor of mortality above and beyond many known risk factors such as demographics, comorbidities, risk behaviors and functional status. The prognostic value of cognition can be potentially useful in informing clinical and policy decision making. |
| Keyword | cognitive aging; joint growth and survival model; random forest; structural equation modeling; survival analysis; survival trees |
| Language | English |
| Part of collection | University of Southern California dissertations and theses |
| Publisher (of the original version) | University of Southern California |
| Place of publication (of the original version) | Los Angeles, California |
| Publisher (of the digital version) | University of Southern California. Libraries |
| Provenance | Electronically uploaded by the author |
| Type | texts |
| Legacy record ID | usctheses-m |
| Contributing entity | University of Southern California |
| Rights | Zhou, Yan |
| Physical access | The author retains rights to his/her dissertation, thesis or other graduate work according to U.S. copyright law. Electronic access is being provided by the USC Libraries in agreement with the author, as the original true and official version of the work, but does not grant the reader permission to use the work if the desired use is covered by copyright. It is the author, as rights holder, who must provide use permission if such use is covered by copyright. The original signature page accompanying the original submission of the work to the USC Libraries is retained by the USC Libraries and a copy of it may be obtained by authorized requesters contacting the repository e-mail address given. |
| Repository name | University of Southern California Digital Library |
| Repository address | USC Digital Library, University of Southern California, University Park Campus MC 7002, 106 University Village, Los Angeles, California 90089-7002, USA |
| Repository email | cisadmin@dots.usc.edu |
| Archival file | uscthesesreloadpub_Volume71/etd-ZhouYan-101.pdf |
Description
| Title | Page 1 |
| Contributing entity | University of Southern California |
| Repository email | cisadmin@dots.usc.edu |
| Full text | DYNAMIC ANALYSES OF COGNITION AND MORTALITY IN THE OLDEST OLD by Yan Zhou A Dissertation Presented to the FACULTY OF THE USC GRADUATE SCHOOL UNIVERSITY OF SOUTHERN CALIFORNIA In Partial Fulfillment of the Requirements for the Degree DOCTOR OF PHILOSOPHY (PSYCHOLOGY) August 2011 Copyright 2011 Yan Zhou |
