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MICROBIAL DETECTION OF MATERIAL DEFECTS AND WEAKNESS
by
Michael S. Waters
A Dissertation Presented to the
FACULTY OF THE GRADUATE SCHOOL
UNIVERSITY OF SOUTHERN CALIFORNIA
In Partial Fulfillment of the
Requirements for the Degree
DOCTOR OF PHILOSOPHY
(MOLECULAR BIOLOGY)
August 2009
Copyright 2009 Michael S. Waters
Object Description
| Title | Microbial detection of material defects and weakness |
| Author | Waters, Michael S. |
| Author email | mikebiotech@gmail.com; mswaters@usc.edu |
| Degree | Doctor of Philosophy |
| Document type | Dissertation |
| Degree program | Molecular & Computational Biology |
| School | College of Letters, Arts and Sciences |
| Date defended/completed | 2009-05-04 |
| Date submitted | 2009 |
| Restricted until | Unrestricted |
| Date published | 2009-07-23 |
| Advisor (committee chair) | Goodman, Steven D. |
| Advisor (committee member) |
Nealson, Kenneth H. Udwadia, Firdaus E. Finkel, Steven Arbeitman, Michelle |
| Abstract | The current rate of non-biodegradable waste disposal is not sustainable and seriously dangerous to living conditions. The intelligent application of preventative maintenance would dramatically decrease waste disposal and is estimated to save hundreds of billions of dollars annually in the United States alone. By developing new, cheap and non-labor intensive methods for assessing material quality, the potential to reduce the environmental and fiscal costs of waste disposal is increased. This thesis work is focused on developing rapid, simple, high-resolution, cost-effective technology using bacteria to detect defects and weakness in materials. To this end, described here will be: 1) advancements in the usage of Vertical ScanningInterferometry (VSI) to measure through corrosive microbes to their corroding mineral/metal interface; 2) the capacity to use several microbes in the Shewanella genus to specifically detect microscale levels of a corrosive byproduct; 3) the development of biologically interactive tools and methods that are independently capable of measuring mechanical strain fields across a wide range in materials; 4) the bioengineering of microbial biofilms to spatially resolve strain across a surface. Hopefully, each of these burgeoning technologies will be developed and will spawn directions for future interdisciplinary research focused on using environmentally harmonious strategies to improve the overall quality of living while simultaneously decreasing environmental impact. |
| Keyword | VSI; corrosion; interferometry; interface; biofilm; streptococcus; Shewanella; strain; rust; iron oxide |
| Language | English |
| Part of collection | University of Southern California dissertations and theses |
| Publisher (of the original version) | University of Southern California |
| Place of publication (of the original version) | Los Angeles, California |
| Publisher (of the digital version) | University of Southern California. Libraries |
| Provenance | Electronically uploaded by the author |
| Type | texts |
| Legacy record ID | usctheses-m2380 |
| Rights | Waters, Michael S. |
| Repository name | Libraries, University of Southern California |
| Repository address | Los Angeles, California |
| Repository email | http://www.usc.edu/isd/libraries/services/ask_a_librarian/email/ |
| Filename | etd-Waters-3052 |
| Archival file | uscthesesreloadpub_Volume32/etd-Waters-3052.pdf |
Description
| Title | Page 1 |
| Full text | MICROBIAL DETECTION OF MATERIAL DEFECTS AND WEAKNESS by Michael S. Waters A Dissertation Presented to the FACULTY OF THE GRADUATE SCHOOL UNIVERSITY OF SOUTHERN CALIFORNIA In Partial Fulfillment of the Requirements for the Degree DOCTOR OF PHILOSOPHY (MOLECULAR BIOLOGY) August 2009 Copyright 2009 Michael S. Waters |
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