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DEVELOPMENT OF BACK-END PROCESSING SYSTEM
FOR HIGH FREQUENCY ULTRASOUND B-MODE IMAGING
by
Jin Ho Chang
A Dissertation Presented to the
FACULTY OF THE GRADUATE SCHOOL
UNIVERSITY OF SOUTHERN CALIFORNIA
In Partial Fulfillment of the
Requirements for the Degree
DOCTOR OF PHILOSOPHY
(BIOMEDICAL ENGINEERING)
December 2007
Copyright 2007 Jin Ho Chang
Object Description
| Title | Development of back-end processing system for high frequency ultrasound b-mode imaging |
| Author | Chang, Jin Ho |
| Author email | jinhchan@usc.edu |
| Degree | Doctor of Philosophy |
| Document type | Dissertation |
| Degree program | Biomedical Engineering |
| School | Viterbi School of Engineering |
| Date defended/completed | 2007-10-02 |
| Date submitted | 2007 |
| Restricted until | Restricted until 10 Oct. 2008. |
| Date published | 2008-10-10 |
| Advisor (committee chair) | Shung, K. Kirk |
| Advisor (committee member) |
Yen, Jesse T. Cannata, Jonathan Matthew Meng, Ellis F. Kim, Eun Sok |
| Abstract | High frequency ultrasound is capable of providing fine spatial resolution on the order of several tens of micrometers and fine temporal resolution of more than 200 frames per second. These capabilities are applicable to the cardiac imaging of the mouse where the heart rate is 5-10 beats per second. In order to adequately capture the cardiac activity of the mouse, two key elements are required: high-speed acquisition of echo signals (front-end system) and high-speed signal processing functions to extract clinically useful information from the acquired echo signals and to display the information on a monitor in real time (back-end system).; This thesis presents the development of a high speed back-end processing system for high frequency ultrasound B-mode imaging, which requires a very fast computational speed and a very wide bandwidth of data transfer between each functional block. In order to achieve the requirement, a DC canceller, a digital time gain compensator, a novel envelope detector with capability of logarithmic compression, and a digital scan converter (DSC) capable of performing fast coordinate transformation and data interpolation are proposed. In addition, the wide bandwidth of data transfer between the DSC module and an image display module is achieved by using a 64-bit 33 MHz PCI bus.; The operating speed of the developed back-end system was examined by recording the completion time of transferring an image to PC and by acquiring images of a moving object at predetermined speed. Through these experiments, it is shown that the back-end system developed is capable of acquiring up to 400 images consisting of 256-by-256 pixels per second at 100 MHz system clock frequency. At present, its display rate is 95 images per second due to the limitation of a monitor's capability although one thousand scan converted images can be stored in the hard disk of PC. By wire phantom, in vitro pig eye, and in vivo mouse heart imaging experiments, it is verified that the developed system is capable of serving as a backend processing system to maximize benefits of high frequency ultrasound, i.e., a fine spatial and a fine temporal resolution. |
| Keyword | high frequency ultrasound; medical ultrasound imaging System; small animal imaging; envelope detector; digital scan converter |
| Language | English |
| Part of collection | University of Southern California dissertations and theses |
| Publisher (of the original version) | University of Southern California |
| Place of publication (of the original version) | Los Angeles, California |
| Publisher (of the digital version) | University of Southern California. Libraries |
| Type | texts |
| Legacy record ID | usctheses-m861 |
| Contributing entity | University of Southern California |
| Rights | Chang, Jin Ho |
| Repository name | Libraries, University of Southern California |
| Repository address | Los Angeles, California |
| Repository email | cisadmin@dots.usc.edu |
| Filename | etd-Chang-20071010 |
| Archival file | uscthesesreloadpub_Volume29/etd-Chang-20071010.pdf |
Description
| Title | Page 1 |
| Contributing entity | University of Southern California |
| Repository email | cisadmin@dots.usc.edu |
| Full text | DEVELOPMENT OF BACK-END PROCESSING SYSTEM FOR HIGH FREQUENCY ULTRASOUND B-MODE IMAGING by Jin Ho Chang A Dissertation Presented to the FACULTY OF THE GRADUATE SCHOOL UNIVERSITY OF SOUTHERN CALIFORNIA In Partial Fulfillment of the Requirements for the Degree DOCTOR OF PHILOSOPHY (BIOMEDICAL ENGINEERING) December 2007 Copyright 2007 Jin Ho Chang |
