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REPRODUCTIVE FACTORS AND RISK OF B-CELL NON-HODGKIN’S
LYMPHOMAS AMONG WOMEN IN LOS ANGELES
by
Yani Lu
———————————————————————————
A Thesis Presented to the
FACULTY OF THE GRADUATE SCHOOL
UNIVERSITY OF SOUTHERN CALIFORNIA
In Partial Fulfillment of the
Requirements for the Degree
MASTER OF SCIENCE
(APPLIED BIOMETRY AND EPIDEMIOLOGY)
May 2008
Copyright 2008 Yani Lu
Object Description
| Title | Reproductive factors and risk of B-cell non-Hodgkin's lymphomas among women in Los Angeles |
| Author | Lu, Yani |
| Author email | yanilu@usc.edu |
| Degree | Master of Science |
| Document type | Thesis |
| Degree program | Applied Biostatistics & Epidemiology |
| School | Keck School of Medicine |
| Date defended/completed | 2008 |
| Date submitted | 2008 |
| Restricted until | Unrestricted |
| Date published | 2008-04-16 |
| Advisor (committee chair) | Bernstein, Leslie |
| Advisor (committee member) |
Cozen, Wendy Mack, Wendy |
| Abstract | Study Aim: Reproductive patterns have been inconsistently linked to NHL risk. The aim of this study is to identify if these factors affect B-cell NHL risk among women. Methods: We conducted a population-based case-control study in Los Angeles County. A total of 555 histologically confirmed B-cell NHL patients and 555 individually matched control subjects were included. Conditional logistic regression was used to evaluate these associations. Results: Reproductive history factors such as gravidity, parity, and outcome of first pregnancy were not associated with B-cell NHL risk overall or any NHL subtype. A modest association was observed for use of lactation suppressants (OR=0.78, 95% CI=0.56-1.08). The use of diethylstilbestrol (DES) during pregnancy increased the risk of B-cell NHL (OR=2.10, 95% CI=0.71-6.23). Conclusion: Reproductive factors were not associated with the risk of B-cell NHL overall or any subtype. Future studies with greater numbers of NHL subtypes are needed to confirm our study results. |
| Keyword | non-Hodgkin's lymphomas; reproductive factors |
| Geographic subject (city or populated place) | Los Angeles County |
| Language | English |
| Part of collection | University of Southern California dissertations and theses |
| Publisher (of the original version) | University of Southern California |
| Place of publication (of the original version) | Los Angeles, California |
| Publisher (of the digital version) | University of Southern California. Libraries |
| Type | texts |
| Legacy record ID | usctheses-m1104 |
| Rights | Lu, Yani |
| Repository name | Libraries, University of Southern California |
| Repository address | Los Angeles, California |
| Repository email | http://www.usc.edu/isd/libraries/services/ask_a_librarian/email/ |
| Filename | etd-Lu-20080416 |
| Archival file | uscthesesreloadpub_Volume29/etd-Lu-20080416.pdf |
Description
| Title | Page 1 |
| Full text | REPRODUCTIVE FACTORS AND RISK OF B-CELL NON-HODGKIN’S LYMPHOMAS AMONG WOMEN IN LOS ANGELES by Yani Lu ——————————————————————————— A Thesis Presented to the FACULTY OF THE GRADUATE SCHOOL UNIVERSITY OF SOUTHERN CALIFORNIA In Partial Fulfillment of the Requirements for the Degree MASTER OF SCIENCE (APPLIED BIOMETRY AND EPIDEMIOLOGY) May 2008 Copyright 2008 Yani Lu |
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