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APPLICATIONS OF ONE-DIMENSIONAL STRUCTURED NANOMATERIALS
AS BIOSENSORS AND TRANSPARENT ELECTRONICS
by
Fumiaki Ishikawa
A Dissertation Presented to the
FACULTY OF THE GRADUATE SCHOOL
UNIVERSITY OF SOUTHERN CALIFORNIA
In Partial Fulfillment of the
Requirements for the Degree
DOCTOR OF PHILOSOPHY
(MATERIALS SCIENCE)
December 2009
Copyright 2009 Fumiaki Ishikawa
Object Description
| Title | Applications of one-dimensional structured nanomaterials as biosensors and transparent electronics |
| Author | Ishikawa, Fumiaki |
| Author email | fishikaw@usc.edu; fishikaw@gmail.com |
| Degree | Doctor of Philosophy |
| Document type | Dissertation |
| Degree program | Materials Science & Engineering |
| School | Viterbi School of Engineering |
| Date defended/completed | 2009-10-08 |
| Date submitted | 2009 |
| Restricted until | Unrestricted |
| Date published | 2009-10-20 |
| Advisor (committee chair) | Zhou, Chongwu |
| Advisor (committee member) |
Goo, Edward Thompson, Mark |
| Abstract | This dissertation presents applications of one-dimensional structured nanomaterials, carbon nanotubes and In2O3 nanowires, for biosensors and transparent electronics.; Chapter 1 gives the motivation to study applications of one-dimensional structured nanomaterials, and also brief introduction to structure, synthesis, and electronic properties of carbon nanotubes and In2O3 nanowires.; In Chapter 2, introduction and motivation of biosensors using nanotubes/nanowires is given, followed by an overview on important background knowledge and concepts in biosensing.; In Chapter 3, application of carbon nanotube biosensors toward brown tide algae detection is presented. Our devices successfully detected a brown tide marker selectively with real-time response.; In Chapter 4, we demonstrate that In2O3 nanowire biosensors coupled with an antibody mimic protein (Fibronectin, Fn) can be used to detect nucleocapsid (N) protein, a biomarker for severe acute respiratory syndrome (SARS), at concentrations to below the sub-nanomolar range.; In Chapter 5, we develop an analytical method to calibrate nanowire biosensor responses that can suppress the device-to-device variation in sensing response significantly.; In Chapter 6, we investigate the effect of nanotube density on the biosensor performance, and proved that it plays an important role through systematic studies.; In Chapter 7, I propose a future direction of nanobiosensors research, and show preliminary results along the proposed direction. I first present a concept of an ideal bioassay system with a list of requirements for the system, and propose the strategy of multi-integration to establish a system based on nanobiosensors that satisfies all of the requirements.; In Chapter 8, we demonstrate high performance fully transparent transistors based on transfer printed aligned carbon nanotubes on both rigid and flexible substrates. We achieved device mobility as high as 1,300 cm2/Vs on glass substrates, which is the highest among transparent transistors reported so far. We also demonstrated fully transparent PMOS inverters on flexible substrates, and also successfully controlled commercial GaN light–emitting diodes (LEDs) with light intensity modulation of 10^3.; Lastly, a brief summary of this thesis is given in Chapter 9. |
| Keyword | biosensor; nanotube; nanowire; transparent electronics |
| Language | English |
| Part of collection | University of Southern California dissertations and theses |
| Publisher (of the original version) | University of Southern California |
| Place of publication (of the original version) | Los Angeles, California |
| Publisher (of the digital version) | University of Southern California. Libraries |
| Provenance | Electronically uploaded by the author |
| Type | texts |
| Legacy record ID | usctheses-m2677 |
| Rights | Ishikawa, Fumiaki |
| Repository name | Libraries, University of Southern California |
| Repository address | Los Angeles, California |
| Repository email | http://www.usc.edu/isd/libraries/services/ask_a_librarian/email/ |
| Filename | etd-Ishikawa-3344 |
| Archival file | uscthesesreloadpub_Volume26/etd-Ishikawa-3344.pdf |
Description
| Title | Page 1 |
| Full text | APPLICATIONS OF ONE-DIMENSIONAL STRUCTURED NANOMATERIALS AS BIOSENSORS AND TRANSPARENT ELECTRONICS by Fumiaki Ishikawa A Dissertation Presented to the FACULTY OF THE GRADUATE SCHOOL UNIVERSITY OF SOUTHERN CALIFORNIA In Partial Fulfillment of the Requirements for the Degree DOCTOR OF PHILOSOPHY (MATERIALS SCIENCE) December 2009 Copyright 2009 Fumiaki Ishikawa |
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