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MEANINGFUL GAIT SPEED IMPROVEMENT DURING THE FIRST 60 DAYS
POST-STROKE: MINIMAL CLINICALLY IMPORTANT DIFFERENCE
by
Julie K. Tilson
A Thesis Presented to the
FACULTY OF THE GRADUATE SCHOOL
UNIVERSITY OF SOUTHERN CALIFORNIA
In Partial Fulfillment of the
Requirements for the Degree
MASTER OF SCIENCE
(CLINICAL AND BIOMEDICAL INVESTIGATIONS)
December 2009
Copyright 2009 Julie K. Tilson
Object Description
| Title | Meaningful gait speed improvement during the first 60 days post-stroke: minimal clinically important difference |
| Author | Tilson, Julie K. |
| Author email | tilson@usc.edu; jktilson@earthlink.net |
| Degree | Master of Science |
| Document type | Thesis |
| Degree program | Clinical & Biomedical Investigations |
| School | Keck School of Medicine |
| Date defended/completed | 2009-10-05 |
| Date submitted | 2009 |
| Restricted until | Unrestricted |
| Date published | 2009-10-13 |
| Advisor (committee chair) | Azen, Stanley P. |
| Advisor (committee member) |
Sullivan, Katherine J. Xiang, Anny |
| Abstract | Introduction: The purpose of this study was to determine the minimal clinically important difference (MCID) for comfortable gait speed (CGS) for persons between 20 to 60 days post-stroke.; Methods: 283 persons with stroke were prospectively enrolled. CGS and the mRS were measured at 20 and 60-days post-stroke. Improvement ≥1 on the mRS was used to detect meaningful change.; Results: Mean CGS was 0.18 m/s at 20-days and 0.39 m/s at 60-days post-stroke (p<0.001). Among all participants, 47.3% experienced a ≥1 improvement in mRS. MCID was estimated as an improvement of 0.16 m/s in CGS anchored to the mRS.; Conclusions: Patients with sub-acute stroke, who increase gait speed ≥0.16 m/s, are more likely to experience a meaningful improvement in disability level than those who do not. Clinicians can use this reference value to develop goals and interpret progress in patients with sub-acute stroke. |
| Keyword | stroke; walking recovery; gait speed; meaningful change; minimal clinically important difference |
| Language | English |
| Part of collection | University of Southern California dissertations and theses |
| Publisher (of the original version) | University of Southern California |
| Place of publication (of the original version) | Los Angeles, California |
| Publisher (of the digital version) | University of Southern California. Libraries |
| Provenance | Electronically uploaded by the author |
| Type | texts |
| Legacy record ID | usctheses-m2665 |
| Rights | Tilson, Julie K. |
| Repository name | Libraries, University of Southern California |
| Repository address | Los Angeles, California |
| Repository email | http://www.usc.edu/isd/libraries/services/ask_a_librarian/email/ |
| Filename | etd-Tilson-3328 |
| Archival file | uscthesesreloadpub_Volume56/etd-Tilson-3328.pdf |
Description
| Title | Page 1 |
| Full text | MEANINGFUL GAIT SPEED IMPROVEMENT DURING THE FIRST 60 DAYS POST-STROKE: MINIMAL CLINICALLY IMPORTANT DIFFERENCE by Julie K. Tilson A Thesis Presented to the FACULTY OF THE GRADUATE SCHOOL UNIVERSITY OF SOUTHERN CALIFORNIA In Partial Fulfillment of the Requirements for the Degree MASTER OF SCIENCE (CLINICAL AND BIOMEDICAL INVESTIGATIONS) December 2009 Copyright 2009 Julie K. Tilson |
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